3-(Boc-amino)-3-(2-fluorophenyl)propionic acid

3-(Boc-amino)-3-(2-fluorophenyl)propionic acid - Names and Identifiers

Name	3-(Boc-amino)-3-(2-fluorophenyl)propionic acid
Synonyms	RARECHEM AK HT T305 3-N-BOC-3-(2-FLUOROPHENYL)PROPIONIC ACID Boc-3-AMino-3-(2-fluorophenyl)propionic acid 3-(BOC-AMINO)-3-(2-FLUOROPHENYL)PROPIONIC ACID 3-N-BOC-AMINO-3-(2-FLUOROPHENYL)PROPIONIC ACID 3-(Boc-amino)-3-(2-fluorophenyl)propionic acid Boc-DL-3-Amino-3-(2-fluorophenyl)propanoic acid 3-TERT-BUTOXYCARBONYLAMINO-3-(2-FLUORO-PHENYL)-PROPIONIC ACID 3-(tert-Butoxycarbonylamino)-3-(2-fluorophenyl)propionic acid 3-[(tert-butoxycarbonyl)amino]-3-(2-fluorophenyl)propanoic acid
CAS	284493-56-7
EINECS	000-000-0
InChI	InChI=1/C14H18FNO4/c1-14(2,3)20-13(19)16-11(8-12(17)18)9-6-4-5-7-10(9)15/h4-7,11H,8H2,1-3H3,(H,16,19)(H,17,18)

3-(Boc-amino)-3-(2-fluorophenyl)propionic acid - Physico-chemical Properties

Molecular Formula	C14H18FNO4
Molar Mass	283.3
Density	1.214g/cm³
Melting Point	142-144°C
Boling Point	419.8°C at 760 mmHg
Flash Point	207.7°C
Vapor Presure	8.49E-08mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.516
MDL	MFCD02090698

3-(Boc-amino)-3-(2-fluorophenyl)propionic acid - Risk and Safety

Safety Description

24/25 - Avoid contact with skin and eyes.

3-(Boc-amino)-3-(2-fluorophenyl)propionic acid - Introduction

3-(Boc-amino)-3-(2-fluorophenyl)propionic acid is an organic compound with the following properties:
-Appearance: white crystalline powder
-molecular formula: C16H19FNO4
-Molecular weight: 311.33g/mol
-Melting point: 85-87 ° C
-Solubility: Soluble in organic solvents such as chloroform, dichloromethane and ethanol, slightly soluble in water.

This compound is commonly used as a protecting group and mediator in organic synthesis. Its Main uses include the following:
1. As an amino protecting group: Boc Group (tert-butyloxycarbonyl group) can protect the amino group to make it difficult to react, thereby ensuring the progress of the desired reaction.
2. As a synthetic intermediate: can be used for the synthesis of compounds with active amino groups, such as drug intermediates, polypeptide compounds.

in terms of preparation method, the synthesis of 3-(Boc-amino)-3-(2-fluorophenyl)propionic acid is generally completed by multi-step reaction. First, amino propionic acid is reacted with Boc anhydride to give 3-(Boc-amino) propionic acid. Then, Chlorobenzene was used to react with Boc-aminopropionate, and then hydrolyzed to obtain the final product 3-(Boc-amino)-3-(2-fluorophenyl)propionic acid.

Regarding safety information, this compound needs to be stored properly, avoiding contact with strong oxidants and strong acids. During operation, attention should be paid to avoid inhalation, ingestion and skin contact to avoid dust generation. Personal protective equipment such as protective gloves, safety glasses and protective masks should be worn when necessary. If it is taken by mistake or accidentally enters the eyes or skin, rinse immediately with plenty of water and seek medical treatment.

Last Update：2024-04-10 22:41:03